McCormick School of Engineering (2022)
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Revealing the rules behind virus scaffold construction (2019)
March 19, 2019 by Alex Gerage, Northwestern University Researchers used a technique called SyMAPS to analyze multiple amino acid changes within the MS2 virus particle. Credit: Northwestern University
A team of researchers including Northwestern Engineering faculty has expanded the understanding of how virus shells self-assemble, an important step toward developing techniques that use viruses as vehicles to deliver targeted drugs and therapeutics throughout the body.
By performing multiple amino acid substitutions , the researchers discovered instances of epistasis, a phenomenon in which two ...